Proton Pump Inhibitors 1

Wednesday, August 29, 2012

Proton pump inhibitors are a group of medications that decreases the amount of acid in the stomach and intestines. Doctors prescribe PPIs to treat people with GERD, ulcers in the stomach or intestine, or other digestive disorders that may cause excess stomach acid. Dr. Edward Hill tells us more about PPIs in todays 60 Second Housecall.

Dr. Hill:

Proton pump inhibitors, or PPIs, are a group of medications that decrease the amount of acid in the stomach and intestines. Doctors prescribe PPIs to treat people with GERD, ulcers in the stomach or intestine or other digestive disorders that may cause excess stomach acid.

The proton pump inhibitors work by completely blocking the production of stomach acid. They do this by inhibiting a system in the stomach known as the proton pump.

Doctors may prescribe using PPIs alone, or in combination with antacids. PPIs may also be used in combination with certain antibiotics when treating Helicobacter pylori infection, which is thought to be one of the main causes of recurring stomach ulcers.

PPIs are similar in how they work, and there is no evidence that one is more effective than another. However, they differ in how they are broken down by the liver and how they interact with other medications. Also, the effects of some PPIs may last longer than others, and may be taken less frequently.

For North Mississippi Medical Center, Im Dr. Edward Hill.