Proton Pump Inhibitors 2

Thursday, August 30, 2012

Proton pump inhibitors appear to be safe, but there are some possible safety issues and side effects with long-term use of PPIs. Dr. Edward Hill explains more about PPIs and their use in todays 60 Second Housecall.

Dr. Hill:

Proton pump inhibitors, or PPIs, are medicines used to treat acid reflux and stomach ulcers.

Using PPIs for too long can lead to side effects, such as:

Hip fracture


Diarrhea from an infection

Rebound indigestion, which are worsened symptoms after you stop using PPIs

Talk to your doctor about how long you should take a PPI. PPIs can affect how other medicines work. These medicines include clopidogrel, which prevents blood clots, and iron supplements. Make sure your doctor knows if you are taking these medicines.

There are over-the-counter medicines you can take for acid reflux or stomach ulcers. They are called H2 blockers. Talk to your doctor about whether they can help your symptoms.

Other ways to treat reflux symptoms include changing your diet. Elevating the head of your bed six to eight inches can also help. You should avoid alcohol, peppermint, caffeine, and nonsteroidal anti-inflammatory drugs, such as ibuprofen. Also, do not smoke, exercise a lot after eating or eat right before bedtime.

For North Mississippi Medical Center, Im Dr. Edward Hill.